3Biome

Ingredient Research

Bacillus Coagulans

Bacillus Coagulans

Ninety eight percent of subjects in the [bacillus coagulans] group achieved normal stool consistency as compared to placebo (74%). Moreover, there was relief from [...] incomplete evacuation, painful defecation and abdominal pain associated with constipation in [the bacillus coagulans] group as compared to placebo.

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Madempudi RS, Neelamraju J, Ahire JJ, Gupta SK, Shukla VK. Probiotics Antimicrob Proteins. 2020 Jun;12(2):335-342.

Gupta AK, Maity C. Medicine (Baltimore). 2021 Jan 22;100(3):e23641.

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Madempudi RS, Ahire JJ, Neelamraju J, Tripathi A, Nanal S. Sci Rep. 2019 Aug 21;9(1):12210.

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Hun L. Postgrad Med. 2009 Mar;121(2):119-24.

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Dolin BJ. Methods Find Exp Clin Pharmacol. 2009 Dec;31(10):655-9.

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Rogha M, Esfahani MZ, Zargarzadeh AH. Gastroenterol Hepatol Bed Bench. 2014 Summer;7(3):156-63.

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Gupta AK, Maity C. Medicine (Baltimore). 2021 Jan 22;100(3):e23641.

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Rogha M, Esfahani MZ, Zargarzadeh AH. Gastroenterol Hepatol Bed Bench. 2014 Summer;7(3):156-63.

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Zhang T, Zhang C, Zhang J, Sun F, Duan L. Front Cell Infect Microbiol. 2022 Apr 1;12:859967.

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Bacillus Subtilis

Bacillus Subtilis

Oral doses [of bacillus subtilis] significantly decreased the Bristol Stool Scale score and stool frequency, and also significantly improved abdominal sounds. [...] This study shows that [bacillus subtilis] could be effective for [...] loose stools.

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Hatanaka M, Yamamoto K, Suzuki N, Iio S, Takara T, Morita H, Takimoto T, Nakamura T. Benef Microbes. 2018 Apr 25;9(3):357-365.

Li SR, Wang HH, Wu ZY, Liu RH, Tong MH, Wang CH, Wang RL, Zhao HC, Wei W. Zhonghua Yi Xue Za Zhi. 2012 Nov 13;92(42):2955-60.

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Inatomi T, Honma M. Sci Rep. 2021 Dec 16;11(1):24098.

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Rui X, Ma SX. Medicine (Baltimore). 2020 Jun 5;99(23):e20631.

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Chen Z, Feng J, Hu S, Hua Y, Ma S, Fu W, Yang Q, Zhang X. Dig Dis Sci. 2021 Nov 19.

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Pi X, Teng W, Fei D, Zhao G, Liu W. Front Cell Infect Microbiol. 2022 Feb 10;12:821662.

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Urdaci MC, Lefevre M, Lafforgue G, Cartier C, Rodriguez B, Fioramonti J. Front Microbiol. 2018 Jul 10;9:1537.

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Bacillus Clausii

Bacillus Clausii

[Bacillus clausii reduces] onset of diarrhea and related severity symptoms including abdominal discomfort and pain, bloating and flatulence. [Bacillus clausii] may be recommended as a live bio-therapeutic agent for improving clinical pathophysiology of gastrointestinal ailments.

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Maity C, Gupta AK. Heliyon. 2021 Sep 15;7(9):e07993.

Ianiro G, Rizzatti G, Plomer M, Lopetuso L, Scaldaferri F, Franceschi F, Cammarota G, Gasbarrini A. Nutrients. 2018 Aug 12;10(8):1074.

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Plomer M, Iii Perez M, Greifenberg DM. Infect Dis Ther. 2020 Dec;9(4):867-878.

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Chang CW, Chen MJ, Shih SC, Chang CW, Chiau JC, Lee HC, Lin YS, Lin WC, Wang HY. Medicine (Baltimore). 2020 May;99(19):e20098.

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de Castro JA, Guno MJV, Perez MO. Trop Dis Travel Med Vaccines. 2019 Jul 23;5:14.

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Sudha MR, Jayanthi N, Pandey DC, Verma AK. Benef Microbes. 2019 Mar 13;10(2):149-154.

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